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Acute lymphoblastic leukemia is a type of cancer in which the bone marrow produces too many immature white blood cells
Activation of a protein called STAT5 causes competition among others that leads to acute lymphoblastic leukemia ALL.
According to new study, competition among some proteins causes an imbalance that leads to leukemia .
Using a drug that will stop the initial activation of STAT5 and reverse the natural balance of protein will leads to effective treatment of acute lymphoblastic leukemia.
Researchers used innovative methodology by combining mouse models and patience samples in high-throughput DNA sequencing, epigenetic and proteomic analysis and discovered that patients with a high ratio of imbalance proteins of STAT5 to IKAROS or NF-KB had worse prognosis.