Before conception can take place in mammals, the semen and the egg must be in good condition. Male and female mammals have to contribute to conception before it can take place.
Researcher in Washington State University has found that uterus in female mice has enzymes that can break semen into watery form and make it easier to swim for conception to take place.
Female mice produce the enzyme using estrogen to cause the process of breaking down the semen. Lack of gene to induce the process will leads to failure of the semen in the uterus.