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Scientists from Singapore has discovered new way cancers escape the body’s immune system, looking at gastric cancer GC. In gastric cancer, gene promoters are dysregulated in a way that is different from tumour’s antigenic profile to evade the body’s immune system.
Epigenetic is a process by which a cell’s DNA is chemically changed by the environment, to change gene expression.
Creating comprehensive epigenetic profiles for gastric cancer and normal tissue from the same parent shows that some promoters specifically changed in gastric cancer tissues.
Researchers found out that gene variants can cause cancer growth, the use of less immunogenetic variants can enhance the tumour to bypass the host’s immune system.
