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Fatty diet and obesity destroy liver immune system and result in type 2 diabetes.
Researchers at Toronto General Hospital Research Institute used mice cells and human livers to discover why liver of diabetes patients produce much glucose.
They discovered that obesity and fatty diet increased blood sugar, liver cells become pathogenic and destroy immune system.
Researchers fed mice with fatty diet for 4 months, they compared them with other mice and discovered that increased triglycerides in their blood and increase in CD8+ T cells in the liver.
The CD8+ T cells caused an inflammatory to bacterial components that moved to liver from the gut through the blood.
