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The composition and structure of the vaginal microbiome may influence susceptibility to adverse pregnancy outcomes.
Decrease in the diversity and structure of vaginal microbes of pregnant women between the first and second trimesters is related with preterm birth.
Women at risk of preterm birth are treated with broad strokes, including hormones or antibiotics, bed rest and a surgical procedure that closes the cervix during pregnancy.
Stable amount and diversity of vaginal microbes leads to full term pregnancy while pregnant women who delivered their babies early experienced decreases in the amount and diversity of such microbes between the first and second trimesters.