Male infertility contributes to fifty percent of all infertility cases. In 6-10% the cause is an urogenital infection. The
main cause of inflammatory disease in the male genital tract are sexually transmitted pathogens.
The diagnostic evaluation of urogenital infections in most patients with infertility is hindered by an asymptomatic primary chronic disease course.
Asymptomatic inflammatory reactions are found in 25% of men who undergo testicular biopsy for infertility.
It was discovered that after acute inflammation of the epididymis, in 10% of cases no sperm was found in the ejaculate in the long term, and in 30% the number of spermatozoa were reduced; in 60% of men affected by an infection of the epididymis, the testes were affected too.
In such cases, testicular atrophy with permanent loss of spermatogenesis is a much feared complication.
If pathogens are detected in the male genital tract, eradicating antibiotic therapy is indicated.
However, this dies not guarantee that the quality of sperm will not be permanently affected or that the outcome will not be infertility.