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Alzheimer’s gene and diet rich in fat and sugar can increase the risk of developing the disease.
ApoE4 gene that affects memory is the major cause of Alzheimer’s disease.
Genes, diet, environment and lifestyle determine risk of developing any disease including Alzheimer’s disease.
ApoE4 and ApoE3 are two variants of a gene that codes for a protein, apolipoprotein E, which combine fat and cholesterol and take them to the body’s lymphatic and circulatory systems and to the brain.
The ApoE4 causes an inflammation, Alzheimer’s diseases and cardiovascular disease while ApoE3 does not increase risk of the disease. ApoE4 is present in about fifteen percent of people. Alzheimer’s affects more women than men.
Fatty acids like palmitic acid can cause inflammation in the brain because they can go into the brain and affect glia. Glia is responsible for immune response in the brain, poor diet can make it less effective in protecting the brain.