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In an analysis of one of the largest electronic medical records databases in the world, researchers found that patients with acne had a significantly increased risk of developing major depression, but only in the first 5 years after being diagnosed with acne. The British Journal of Dermatology analysis included data from The Health Improvement Network (THIN) (1986-2012), a large primary care database in the United Kingdom.
The investigators found that the risk for major depression was highest within 1 year of acne diagnosis a-63% higher risk compared with individuals without acne and decreased thereafter. The results indicate that it is critical that physicians monitor mood symptoms in patients with acne and initiate prompt treatment for depression or seek consultation from a psychiatrist when needed.
This study highlights an important link between skin disease and mental illness. Given the risk of depression was highest after the first time a patient presented to a physician for acne concerns, it shows how impactful human skin can be towards overall mental health.