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Microbiome affects almost every aspect of human health; and its microbial composition which varies may hold the key to everything from weight gain to moods. The variation starts with differences in genes; but a large-scale study conducted at the Weizmann Institute of Science challenges this idea and provides evidence that the connection between microbiome and health may be different.
Genetics plays a major role in determining microbiome variation among people. Genes determine the environment microbiome occupies, and each particular environment allows certain bacterial strains to thrive. Host’s genetics play a very minor role in determining microbiome composition.
Diet and lifestyle are the most dominant factors shaping human microbiome composition. Microbiome populations are shaped by genetics because they interact with genes to modify human health. It is impossible to change genes, change in lifestyle can change the composition of different kinds of bacteria in human bodies.
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