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Plenvu (polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride) is a lower-volume, polyethylene glycol based osmotic laxative indicated for cleansing of the colon (bowel preparation) before colonoscopy.
Two doses of Plenvu are required for a complete preparation for colonoscopy, using a “Two-Day” or “One-Day” dosing regimen.
Two-Day Dosing Regimen: Dose 1 is taken the evening before the colonoscopy (approximately 4 pm to 8 pm) and Dose 2 is taken the next morning (approximately 12 hours after the start of Dose 1).
One-Day Dosing Regimen: Dose 1 is taken the morning of the colonoscopy (approximately 3 am to 7 am) and Dose 2 a minimum of 2 hours after the start of Dose 1. Plenvu must be reconstituted in water prior to ingestion and additional clear liquids must be consumed after each dose. Drink only clear liquids before, during, and after taking Plenvu, until 2 hours before the colonoscopy to help prevent dehydration.
Do not take oral medications within one hour of starting each dose. Do not take or drink laxative, alcohol, milk, anything colored red or purple or any other foods containing pulp material while you are taking Plenvu. Side effects of plenvu are; nausea, vomiting, dehydration and abdominal pain, serious loss of body fluid-dehydration and changes in blood salts -electrolytes in the blood. Drink enough water to prevent dehydration.
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