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The first randomized, controlled trial testing carbon dioxide gas injections (carboxytherapy) to reduce belly fat found the new technique eliminates fat around the stomach. However, the changes were modest and did not result in long-term fat reduction, according to the Northwestern Medicine study.
According to Dr. Murad Alam, vice chair of dermatology at Northwestern University Feinberg School of Medicine and a Northwestern Medicine physician, Carboxytherapy could potentially be a new and effective means of fat reduction.
Current technologies routinely used for non-invasive fat reduction are cryolipolysis, high intensity ultrasound, radiofrequency, chemical adipocytolysis and laser-assisted fat reduction. The Northwestern study consisted of 16 adults who were not overweight (body mass of 22 to 29) and were randomized to get weekly carbon dioxide gas injection to one side of their abdomens and a sham treatment on the other side once a week for five weeks.
A high-resolution ultrasound detected a reduction in superficial fat after five weeks but not at 28 weeks. The patients’ body weight did not change over the course of the study. The difference was not maintained at six months suggests the treatment stimulated a temporary metabolic process that reduced the size of fat cells without inducing cell death.
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