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Cancer starts when gene changes make one cell or a few cells divide in an uncontrolled way, this can occur in any part of the body. There are more than 210 different types of cancer, cancers are divided into groups according to the type of cell they start from. They include:
carcinomas, lymphomas, leukaemias, brain tumours and sarcomas.
Researchers have used lab technology called mass spectrometry to study the proteins expressed by human cancer cells. The advance, which is described in a new Molecular Oncology article, allows for the quantitation of thousands of tumour proteins over the course of several hours.
The strategy was used to identify several proteins that were over-expressed in a rare form of bladder cancer that did not respond to chemotherapy. The findings reveal that proteomics–the large scale study of all proteins in a given system has the potential to quickly provide robust personalised therapeutic options for cancer patients.
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