Posted by 
Osteoarthritis is a form of arthritis caused by the inflammation, breakdown, and eventual loss of cartilage in the joints. It is a common cause of joint damage in the hands, hips, knees and lower back. It occurs when the cartilage that cushions bones in the joints breaks down and wears away, causing the bones to rub against one another.
In a study led by OMRF scientist Tim Griffin, Ph.D., researchers found that the carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice. Several factors like high-impact physical jobs, joint injuries, age, genetics and extra body weight are the major contributors.
Obesity is one of the most significant factors for developing disease in the knee joint, therapeutic strategies to prevent or treat obesity-associated OA are limited because of the uncertainly about the cause of the disease. Researchers placed groups of mice on different high-fat diets. However, over time, they observed that the carbohydrate makeup of the rodents’ low-fat control diet was enough to alter their chances of developing OA.
Changing the amount of sucrose -table sugar and fiber in the diet altered OA pathology in the rodents. The high-sucrose diet increased signs of joint inflammation, while the high-fiber diet caused changes in cartilage genes and cellular stress-response pathways. There are so many OA-related differences between the two high-carb diets even though body weight and body fat were the same.