Skin cancer is the most common cancer, having multiple incidences of a common type of skin cancer increases the risk of developing a range of other cancers. Exposing skin regularly to ultra violet light damages DNA and can eventually lead to cancer. Many internal cancers do not produce symptoms until they are at an advanced stage. Basal cell carcinoma may predict the risk of developing other types of cancer.
Researchers from Stanford University School of Medicine in California recently investigated how the number of basal cell carcinoma occurrences might impact an individual’s future cancer risk. Researchers followed different people who had been treated for unusually frequent basal cell carcinomas to see whether these people had any mutations in the proteins responsible for DNA damage.
They discovered that about 20 percent of the people with frequent basal cell carcinomas have a mutation in one of the genes responsible for repairing DNA damage against 3 percent of the general population. Those who develop six or more basal cell carcinomas during a 10-year period are about three times more likely than the general population to develop other, unrelated cancers.
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