Posted by 
E-cigarette was Introduced to the market in 2004, the handheld electronic devices heat a liquid, usually containing nicotine, into an aerosol that the user inhales. Different flavors of liquids are available such as fruit, chocolate and candy. More carcinogens arise from the combustion of tobacco in regular cigarettes than from the vapor of e-cigarettes. Vaping is the use of e-cigarette, vaping may modify the genetic material- DNA in the oral cells of vapers which could increase cancer risk.
To characterize chemical exposures during vaping, the researchers recruited five e-cigarette users. They collected saliva samples before and after 15-minute vaping session and analyzed the samples for chemicals that are known to damage DNA. To evaluate possible long-term effects of vaping, the team assessed DNA damage in the cells of the volunteers’ mouths. The researchers used mass-spectrometry-based methods they had developed previously for a different study in which they evaluated oral DNA damage caused by alcohol consumption.
They identified three DNA-damaging compounds: formaldehyde, acrolein and methylglyoxal, whose levels increased in the saliva after vaping. Compared with people who don’t vape, four of the five e-cigarette users showed increased DNA damage related to acrolein exposure. DNA adduct occurs when toxic chemicals, such as acrolein, react with DNA. If the cell does not repair the damage so that normal DNA replication can take place, cancer could result.