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Artificial sweeteners and sport supplements were found to be toxic to digestive gut microbes. Relative toxicity of six artificial sweeteners (aspartame, sucralose, saccharine, neotame, advantame, and acesulfame potassium-k) and 10 sport supplements containing these artificial sweeteners.
The bacteria found in the digestive system became toxic when exposed to concentrations of one mg./ml. of the artificial sweeteners. Researchers modified bioluminescent E. coli bacteria, which luminesce when they detect toxicants and act as a sensing model representative of the complex microbial consumption of artificial sweeteners adversely affects gut microbial activity which can cause a wide range of health issues.
Artificial sweeteners are used in food products and soft drinks with reduced sugar content. Many people consume this added ingredient without their knowledge. Moreover, artificial sweeteners have been identified as environmental pollutants, and can be found in drinking and surface water, and groundwater aquifers. The tested bioluminescent bacterial panel can potentially be used for detecting artificial sweeteners in the environment.