Type 1 diabetes can be treated under the skin

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Researchers have demonstrated that the space under our skin might be an optimal location to treat type 1 diabetes T1D. Transplanting of healthy pancreatic cells under the skin to produce insulin for blood glucose regulation.

Insulin-making beta cells, located in regions of the pancreas known as pancreatic islets, are damaged in type 1 diabetes patients, implanting healthy new cells could restore insulin function.

Pancreatic islets are scattered throughout the pancreas in between other pancreatic cells that secrete digestive enzymes. The space under the skin has a large area so that it can support many islets.

Researchers injected healthy pancreatic islets under the skin and found that normal blood sugar levels could be restored within three weeks.

Pancreatic islets comprise one per cent of the pancreas, but require twenty percent of the blood flow to the organ, adequate blood flow to the islets will make it work properly.
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