Effects of brain tickle on memory

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Tickling the brain with low-intensity electrical stimulation in a specific area can improve verbal short-term memory. Mayo Clinic researchers report their findings in Brain. The researchers found word recall was enhanced with stimulation of the brain’s lateral temporal cortex, the regions on the sides of the head by the temples and ears.

Patients recalled more words from a previously viewed list when low-amplitude electrical stimulation was delivered to the brain. One patient reported that it was easier to picture the words in his mind for remembering.

Human memory for language information can be improved by directly stimulating this underexplored brain area. Memory impairments are a prevalent, costly problem in many brain diseases. Medication and behavioral therapies have limited effectiveness in many cases. While electrical stimulation of the brain is emerging as potential therapy for a wide range of neurological and psychiatric diseases, little is known about its effect on memory.

The memory testing was done with patients undergoing evaluation for surgery to address seizures. These patients agreed to have their memory investigated using the electrodes implanted in their brains for surgical evaluation. It is common for people with epilepsy to have memory problems because the brain circuits that underlie memory function often are affected by epilepsy.

In the study, patients were instructed to read a list of words-one at a time from a computer screen. Electrical stimulation was applied some of this time. Patients then attempted to freely recall the words in any order. The researchers found enhanced memory performance in the patients with stimulation of the lateral temporal cortex but not among those with the other brain regions stimulated.
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