Antidepressant may stop liver disease

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Primary Biliary Cholangitis (PBC) is a rare, incurable liver disease, which can be fatal if untreated. It is a chronic disease in which the bile ducts in the liver are slowly destroyed. Bile is a fluid made in the liver. It aids digestion and gets rid of cholesterol, toxins and worn-out red blood cells. PBC is more commonly diagnosed in women, usually between the ages of 40-60. Symptoms can include severe fatigue and itchiness.

A drug usually prescribed for depression appears to effectively stop progression of PBC. It slowly destroys the small bile ducts of the liver. Once damaged, the liver can “fill up” with materials the body is trying to excrete, damaging the liver and leading to permanent scarring. According to Swain, the head of the Division of Gastroenterology and Hepatology in the Department of Medicine, PBC slowly destroys the small bile ducts of the liver.

Once damaged, the liver can “fill up” with materials the body is trying to excrete, damaging the liver and leading to permanent scarring,  Mirtazapine has significant effects on the immune system which appear to be protective to the liver. Primary biliary cholangitis, previously called primary biliary cirrhosis, is a chronic disease in which the bile ducts in your liver are slowly destroyed. Bile is a fluid made in your liver. It aids with digestion and helps your body get rid of cholesterol, toxins and worn-out red blood cells.

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