Infertile men may develop prostate cancer

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According to a Swedish study, infertile men may develop aggressive early-onset prostate cancer, those who are unable to have children naturally or via IVF are 47 per cent more likely to develop the cancer, men under 50 have higher risk. Undiagnosed prostate tumours may cause infertility, while low testosterone levels could lead to the development of both conditions.

Researchers, from Lund University, analysed men and their first born children in Sweden between 1994 and 2014. Information was taken from birth, cancer and assisted reproduction registers. Men who underwent intracytoplasmic sperm injections (ICSI) were compared against those who became parents naturally or via IVF. ICSI involves injecting a single sperm into an egg, mixes sperm with eggs and allows them to fertilise.

Men seeking fertility treatment should be screened for cancer, men who have ICSI are at a significantly higher risk of early-onset prostate cancer. The fertility treatment could be used as a screening tool for prostate cancer diagnoses. Among infertile women undergoing IVF after two unsuccessful attempts, 54.3 per cent become pregnant and 51.4 per cent go on to have a live birth after receiving the growth hormones estradiol and progesterone, a study found. Estradiol and progesterone are thought to improve blood flow to the lining of the uterus, preparing it for egg implantation.

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